RECENT CITATIONS: FLUOROKINE® MAP MULTIANALYTE PROFILING

Many researchers have taken advantage of the high throughput capability and flexibility afforded by R&D Systems Fluorokine MAP
Multianalyte Profiling Kits. These time-saving bead-based assays allow for the measurement of multiple analytes in a single small sample using the Luminex® 100™, Luminex 200™, or Bio-Rad® Bio-Plex™ detection instruments. Currently R&D Systems offers bead sets for measuring the levels of cytokines, chemokines, MMPs, obesity-related factors, adhesion molecules, growth factors, and more. Also available are multiplex development reagents for the creation of user-defined assays.

• Human Cytokine Panel A

  (Base Kit Catalog # LUH000)
  John, C.C. et al. (2006) Low levels of RANTES are associated with mortality in children with cerebral malaria. J. Infect. Dis. 194:837.
  Sample Type: Human serum

  Molecule	Microparticle Catalog #
  IFN-gamma	LUH285
  IL-1 beta	LUH201
  IL-6	LUH206
  TNF-alpha	LUH210
  CCL3/MIP-1 alpha	LUH270
  CCL4/MIP-1 beta	LUH271
  CCL5/RANTES	LUH278

  
  
• Jewett, A. et al. (2006) Coengagement of CD16 and CD94 receptors mediates secretion of chemokines and induces apoptotic death of naïve natural killer cells. Clin. Cancer Res. 12:1994.
  Sample Type: Human NK cell supernatant
  

  Molecule	Microparticle Catalog #
  IL-4	LUH204
  IL-5	LUH205
  IL-6	LUH206
  IL-1 beta	LUH201
  IL-10	LUH217
  IFN-gamma	LUH285

  
  

• Mouse Cytokine Panel

  (Base Kit Catalog # LUM000)
  Altemeier, W.A. et al. (2005) Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J. Immunol. 175:3369.
  Sample Type: Mouse BAL fluid
  

  Molecule	Microparticle Catalog #
  MIP-2	LUM452
  KC	LUM453
  IL-1 beta	LUM401
  IL-6	LUM406
  IL-10	LUM417
  IL-12 p70	LUM419
  TNF-alpha	LUM410
  GM-CSF	LUM415
  IFN-gamma	LUM485

  
  
• Meyer, U. et al. (2006) The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. J. Neurosci. 26:4752.
  Sample Type: Mouse serum and fetal brain
  homogenate
  

  Molecule	Microparticle Catalog #
  IL-1 beta	LUM401
  IL-6	LUM406
  TNF-alpha	LUM410
  IL-10	LUM417

• Human MMP Panel

  (Base Kit Catalog # LMP000)
  Menon, R. et al. (2006) Salivary proteinase activity: a potential biomarker for preterm premature rupture of the membranes. Am. J. Obstet. Gynecol. 194:1609.
  Sample Type: Human saliva
  

  Molecule	Microparticle Catalog #
  MMP-1	LMP901
  MMP-2	LMP902
  MMP-3	LMP513
  MMP-7	LMP907
  MMP-9	LMP911
  MMP-12	LMP919
  MMP-13	LMP511

  
  

• Multiplex Development Kit

  
  (Base Kit Catalog # LDS000)
  Johannisson, A. et al. (2006) Simultaneous detection of porcine proinflammatory cytokines using multiplex flow cytometry by the xMAP® technology. Cytometry A 69A:391.
  Sample Type: Porcine serum and heparin plasma
  

  Molecule	*Capture/Detection Antibody Catalog #	Microparticle Catalog #
  TNF-alpha	MAB6902/BAF690	LDS002
  IL-8	MAB535/BAF535	LDS004
  IL-1 beta	MAB6811/BAF681	LDS005

* Not included with development kits