Browse by Research Topic
Neurotransmitter Receptors, Ion Channels, & Transporters
Neurotransmitter receptors are expressed on the surface of post-synaptic cells to bind ligand-specific neurotransmitters and hormones. They are also expressed on pre-synaptic cells to provide feedback mechanisms and attenuate excessive neurotransmitter release. The majority of neurotransmitter receptors are integral membrane proteins with seven transmembrane domains, commonly coupled to G-proteins. Binding of a ligand to its specific neurotransmitter receptor may result in the activation of a myriad of cell signal transduction pathways and modulation of ion channel homeostasis. R&D Systems offers quality products for experiments focused on the role of dopamine, gamma-aminobutyric acid (GABA), glutamate, N-methyl-D-aspartic acid (NMDA), thrombin and more.