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Adult Tissue-derived Precursor Cells

Recent advances in the field of stem cell research include the discovery of adult stem cells in adipose tissue, muscle, and skin. The identification of adult stem cells has important implications for regenerative therapies to combat disease. Body fat has been shown to contain adipopose-derived precursor cells (ADPC) which are multipotent and have the potential to aid nerve repair. In addition, a regenerative approach is relevant to repair injured, aged, and diseased muscle. Normal repair and exercise-induced cellular hypertrophy in muscle is mediated by satellite cells. However, skeletal muscle also contains a small population of multipotent stem cells. Skeletal muscle-derived precursor cells may play a role in forming new muscle, blood, and connective tissues. The dermis is another tissue which has recently been shown to contain stem cells that can differentiate into both neural and mesodermal lineages. Skin-derived precursor cells are believed to migrate to the skin during embryogenesis, where they retain their multipotent capacity into adulthood.


Skeletal Muscle-derived Precursor Cells

Skin-derived Precursor Cells