Cultrex® Basement Membrane Extract is a soluble basement membrane extract of the Engelbreth-Holm-Swarm (EHS) tumor that gels at 37°C to form a reconstituted basement membrane. It consists of laminin I, type IV collagen, entactin, and heparin sulfate proteoglycan. Cultrex Basement Membrane Extract can be used to promote and maintain a differentiated phenotype of cell cultures such as epithelial cells, endothelial cells, glandular cells, neurons, and smooth muscle cells. It has been employed in assays evaluating angiogenesis, tumor cell invasion, and tumorigenicity.

• Cultrex BME Products
• Cultrex BME Functional Assay

Figure 1. Capillary Formation. SVEC4-10 cells incubated 24 hours at 37°C with 5% FBS and Cultrex® BME		Figure 2. Rat aortic ring assay. Rat aorta incubated 6 days at 37°C with 10% FBS and Cultrex® BME