Product Category
DNA Damage Repair Substrates
DNA repair enzymes are necessary for the repair of errors introduced during DNA replication or recombination or as a result of treatment with exogenous genotoxic agents. These enzymes can be used in vitro to detect specific forms of DNA damage or for repair assays. The DNA Damage Repair Substrates are oligonucleotides that contain specific mutations which are recognized and cleaved by some of the following DNA repair enzymes. These substrates can serve as positive controls for DNA repair assays.
DNA Damage Repair Substrates
- 8-oxo-dG Oligonucleotide* (Catalog # 3850-100-OL)
Sequence: GAACTAGTGOATCCCCCGGGCTGC
Application: Suitable substrate for E. coli Fpg or human OGG1.
*All oligonucleotides are provided with a complementary strand and should be annealed to form suitable substrates for the indicated enzymes.