Product Category

Mouse Cytokine Antibody Array, Panel A

Introduction

R&D Systems Mouse Cytokine Array, Panel A (Catalog # ARY006) is a rapid, sensitive, and economical tool used to simultaneously detect the relative levels of 40 different cytokines, chemokines, and more in a single sample. No specialized equipment is necessary

Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample.
CXCL13/BLC/BCA-1 IL-4 M-CSF
C5a IL-5 CCL2/JE/MCP-1
G-CSF IL-6 CCL12/MCP-5
GM-CSF IL-7 CXCL9/MIG
CCL1/I-309 IL-10 CCL3/MIP-1 alpha
CCL11/Eotaxin IL-12 p70 CCL4/MIP-1 beta
ICAM-1 IL-13 CXCL2/MIP-2
IFN-gamma IL-17 CCL5/RANTES
IL-1 alpha IL-23 CXCL12/SDF-1
IL-1 beta IL-27 CCL17/TARC
IL-1ra CXCL10/IP-10 TIMP-1
IL-2 CXCL11/I-TAC TNF-alpha
IL-3 CXCL1/KC TREM-1

General Assay Principle

Carefully selected capture antibodies have been spotted in duplicate on nitrocellulose membranes. Cell culture supernatant, serum, or plasma samples are diluted and mixed with a cocktail of biotinylated detection antibodies. The sample/antibody mixture is then incubated with the array. Any cytokine/detection antibody complex present is bound by its cognate immobilized capture antibody on the membrane. Streptavidin-Horseradish Peroxidase and chemiluminescent detection reagents* are added and a signal is produced in proportion to the amount of cytokine bound.

Kit Contents

  • 4 Array Membranes
  • 4-Well Multi-dish
  • Array Buffers
  • Wash Buffer
  • Antibody Detection Cocktail
  • Streptavidin-HRP
  • Transparency Overlay Template
  • Detailed Protocol

*Chemiluminescence detection substrate not included. For a complete list of the kit contents and necessary materials, please see the Materials Provided/Materials Required sections of the product insert (PDF 116 KB).