The wide dynamic range of protein concentrations present in serum and plasma represents a major challenge for the analysis of the proteome. The range of plasma protein concentrations, from low abundance proteins such as cytokines (pg/mL) to albumin (30-45 mg/mL), represents at least 10 orders of magnitude. Analysis of low abundance proteins by even the most sensitive of methods for proteomics greatly benefits from the removal of high abundance proteins that may interfere with their detection.

Proteome Purify 12 Human Serum Protein Immunodepletion Resin (Catalog # IDR012)
Single-use resin to deplete human serum or plasma of 12 high abundance proteins.

Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin (Catalog # MIDR002)
Single-use resin to deplete mouse serum or plasma from albumin and IgG