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Kirrel2/NEPH3: Products


Kirrel (kin of irregular chiasm-1-like) proteins, also known as the NEPH (nephrin-like) family, are type I transmembrane glycoproteins within the immunoglobulin superfamily. Kirrel1 (NEPH1), Kirrel2 (NEPH3, Filtrin, NLG-1) and Kirrel3 (NEPH2, kirre) share 34 - 44% amino acid (aa) identity, and all interact with nephrin, podocin and the adaptor molecule ZO-1 (1, 4). All can be found in podocytes of the kidney glomerulus, and play a role in barrier function in the slit diaphragm. (2-6). Kirrel1 can also be found in central nervous system neurons, pancreas and placenta, Kirrel2 in pancreatic islet beta cells, brain and lymph nodes, and Kirrel3 in the brain and bone marrow, typically at sites where nephrin is also expressed.

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DESCRIPTIONANTIBODY
APPLICATION (KEY)
CATALOG #
SIZEPRICEQTY 
Mouse Kirrel2/NEPH3 Affinity Purified Polyclonal Ab, Goat IgG WB AF2930 100 µg $359
Human/Mouse Kirrel2/NEPH3 MAb (Clone 318311), Mouse IgG1 WB MAB2564 100 µg $249
Human Kirrel2/NEPH3 Affinity Purified Polyclonal Ab, Sheep IgG WB AF2564 100 µg $359
Human Kirrel2/NEPH3 Biotinylated Affinity Purified PAb, Sheep IgG WB BAF2564 50 µg $390
Mouse Kirrel2/NEPH3 Biotinylated Affinity Purified PAb, Goat IgG WB BAF2930 50 µg $390
Recombinant Human Kirrel2/NEPH3, CF 2564-K2-050 50 µg $319
Recombinant Mouse Kirrel2/NEPH3, CF 2930-K2-050 50 µg $319