Lorazepam

Tocris Bioscience | Catalog # 3087

Ligand at benzodiazepine site
Tocris Bioscience
Discontinued Product
3087 has been discontinued. View all GABA-A Receptor Benzodiazepines products.

Key Product Details

Description

Ligand at benzodiazepine site

Product Description

Ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.

Product Specifications for Lorazepam

Molecular Weight

321.16

Formula

C15H10Cl2N2O2

Storage

Store at RT

Chemical Name

7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one

CAS Number

846-49-1

PubChem ID

3958

InChI Key

DIWRORZWFLOCLC-UHFFFAOYSA-N

SMILES

O=C2C(O)N=C(C3=CC=CC=C3Cl)C1=CC(Cl)=CC=C1N2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.12 100
Ethanol 12.85 40

Preparing Stock Solutions for Lorazepam

The following data is based on the product molecular weight 321.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.11 mL 15.57 mL 31.14 mL
5 mM 0.62 mL 3.11 mL 6.23 mL
10 mM 0.31 mL 1.56 mL 3.11 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Bonavita Tolerance to the sedative effect of L.pam correlates with a diminution in cortical release and affinity for glutamate. Neuropharmacol.

Product Documents for Lorazepam

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Lorazepam

For research use only

Related Research Areas

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