With over 1,400 antibodies that have been validated, our selection of neutralization and blocking antibodies is unmatched. Our commitment to quality antibodies allows you to be confident in your results and help you generate publication-quality data.
By utilizing our selection of in-house manufactured proteins, we are able to leverage our bioassay expertise to ensure that our antibodies block/neutralize the appropriate cellular function. Our assays include proliferation, chemotaxis, protein secretion, adhesion, and in vitro enzyme neutralization. We continuously add new assays to ensure the highest specificity based on the latest research data.
Low Endotoxin Levels
Our neutralizing antibodies are manufactured to ensure low endotoxin levels. Each lot is QC tested for the level of endotoxin and the information is reported on each individual datasheet. You won’t have to worry about endotoxin-induced nonspecific cellular responses.
What Is The Difference Between Blocking And Neutralizing Antibodies?
A blocking antibody binds its target and directly interferes with its function, such as blocking cell adhesion or receptor-ligand binding. A neutralizing antibody binds its target and negates its downstream cellular effects, such as cell proliferation or chemotaxis.
Unable to find a neutralizing antibody for your research? Utilize our scientific expertise in antibody engineering and development. We have the ability to generate new antibodies by using our full length recombinant proteins as well as offer panels of antibodies from our hybridomas so you can screen multiple clones at once. By having the ability to create recombinant antibodies in-house, we can also immortalize your antibody by converting your existing clone to a recombinant antibody or modifying your current antibody to meet your needs.
Take advantage of our ability to perform blocking and neutralizing bioassays in-house. Our scientists in Bioassay Services will work with you to determine and optimize an assay catered to your needs. You will be provided with raw data and a professionally formatted report with a detailed summary of the bioassay protocol that was used.
R&D Systems offers a wide selection of blocking and neutralizing antibodies across many different research areas. Some research areas include Immune Checkpoint Blockade, Chemokine Functions, Angiogenic Factors, and Developmental Factors. Select one of our top targets below, and view our available products.
PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.