Showing 1-10 out of 21 resource results for "ephrin-a5"
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Article
Angiogenesis specifically describes the sprouting of new blood vessels from the existing vasculature. This process requires the formation of endothelial tip cells, highly motile cells that invade the surrounding tissue. 1 Endothelial tip cells guide the direction of new blood vessel growth by
Article
Ephrin-B2 is a 40 kDa transmembrane protein that belongs to the Ephrin ligand family and binds the receptors EphB2, B3, and B4. The involvement of Ephrin-B2 in a range of physiological systems has been described, including vascular, lymphatic, neuronal, and renal development, neurotransmission,
IHC Images
Ephrin-A2 was detected in immersion fixed rat hippocampal neurons using Mouse Ephrin-A2 Antigen Affinity-purified Polyclonal Antibody (green; Catalog # AF603) at 10 µg/mL for 3 hours at room temperature. Glial cells (red) were labeled by using anti-GFAP antibodies. View our protocol for Fluorescent
Article
The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases. 1,2 The ligands are called ephrins. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning (axon guidance) and possibly in cancer. 1
IHC Images
Ephrin-B1 was detected in perfusion fixed frozen sections of mouse kidney using Mouse Ephrin-B1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF473) at 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and
IHC Images
Ephrin-B2 was detected in immersion fixed rat hippocampal neurons using Mouse Ephrin-B2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF496) at 2 µg/mL for 3 hours at room temperature. Cells were stained (red) and counterstained (green). View our protocol for Fluorescent ICC Staining of
Research Areas
Cell migration is influenced by chemodirectants including a large family of receptor tyrosine kinases collectively referred to as Ephs. Ephs are divided into two classes based on their extracellular structure and ligand specificity. Eph receptors that bind preferentially to ephrin-A ligands are
Article
First printed in R&D Systems' 1999 Catalog. Overview The process of development involves a series of steps: an initial evagination or invagination, followed by cell proliferation, migration, and differentiation. A number of molecules impact the processes of proliferation and
Article
Sheddases cleave membrane proteins at the cell surface, releasing soluble ectodomains with altered location and function. Some sheddases are membrane proteins themselves that belong to metalloprotease (ADAM and MMP) or aspartic protease (BACE) families. Their activity can be constitutive or
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