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First printed in R&D Systems' 1997 Catalog. Overview Figure 1. In the brain, OB contacts OB-R in the choroid plexus. OB is then transported into the CSF where it duffuses into the third ventricle and binds to OB-R on arcuate nucleus (AN) neurons. OB binding to AN parvocellular neurons
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Plasmacytoid dendritic cells (pDC) reside in the circulation, extravasate to inflammatory sites, and traffic to draining lymph nodes to initiate adaptive immune responses. Mature pDC induce T cell survival, Th1 bias, cytotoxic T lymphcyte (CTL) activity, natural killer cell (NK) cytotolytic
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