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Powered by Boston Biochem: Products for Proteasome-related Research

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View Larger Graphic The Ubiquitin Proteasome system is essential for cellular protein homeostasis. Abnormal functioning contributes to a number of human pathologies including Parkinson’s Disease, various cancers, Alzheimer’s Disease, and ALS. Finally, inhibiting proteasome activity with small molecules such as Bortezomib and Carfilzomib has proven efficacious in the treatment of...

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Adiponectin & Apoptotic Cell Clearance

Article

Adiponectin, also known as Acrp30, is an adipocyte-specific secreted protein with wide ranging effects on metabolism and inflammation. Adiponectin regulates glucose and fatty acid metabolism, insulin responsiveness, and adipocyte differentiation.1 It has multiple anti-inflammatory properties (Box 1) that distinguish it from other adipocytokines such as leptin, resistin, and visfatin.2 These...

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Airway Inflammation Markers

Technical Resource

Click on these tabs for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study of these cells and molecules. For a broader representation of airway immunity, please view our poster Airway Inflammation in Asthma. Request Airway Inflammation in Asthma...

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Multiplex Analysis of Secreted Biomarkers from Stimulated Natural Killer Cells

Scientific Abstract Posters

R. Fuerstenberg, S. Anderson, K. Brumbaugh, J. Schmidt ABSTRACT NK (natural killer) cells form a branch of the innate immune system that destroys compromised host cells, such as tumor cells or virus infected cells, by recognizing such cells through a “missing self” mechanism. Over the past decade, NK cells have come under greater scrutiny as major regulators of the host’s immune response...

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Parturition & Surfactant Protein A

Article

One out of every eight babies in the United States is born prematurely, yet very little is known about the causes of preterm labor.1 One clue is that labor, both at term and preterm, is associated with an inflammatory response. Amniotic fluid (AF) levels of IL-1ß, IL-6, and TNF-a, as well as numerous other pro-inflammatory cytokines and chemokines, are elevated during labor.2 Further, it appears...

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Unique Luminex® Analytes

Product Highlights

Our unparalleled immunoassay development expertise – our Quantikine® ELISAs are widely recognized as the industry gold standard – allows us to generate and validate antibody pairs capable of detecting analytes that no other company is able to offer. Browse our impressive collection of over 80 analytes in the table below that can only be measured using R&D Systems® Luminex Assays. Build...

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