"vWF-A2" has 5 results in Resources.

Overview of Platelet Adhesion Proteins and Ligands Platelets adhere to the vascular endothelium at sites of endothelial injury where extracellular matrix (ECM) components in the sub-endothelial space are exposed to the circulation. GP family glycoproteins mediate rapid tethering to ECM molecules at these sites. Integrin heterodimers become activated and then provide robust platelet adhesion....

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Activated platelets rapidly release the contents of three distinct types of preformed intracellular vesicles. Dense granules contain phosphates, purines, and bioactive amines. Lysosomes contain glycosidases and acid proteases. Proteins from alpha granule membranes localize to the platelet surface upon granule release and contribute to platelet adhesion and activation. Alpha granules contain a...

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Click on the tabs below for flow cytometry phenotyping suggestions and extended lists of secreted, cell surface, and intracellular markers. Each link will direct you to our product offerings for the study of these cells and molecules. For a broader representation of atherosclerosis, please view our poster Atherosclerosis Disease Progression. Request Poster   Myeloid...