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Platelet Adhesion Proteins and Ligands

Pathways

Overview of Platelet Adhesion Proteins and Ligands Platelets adhere to the vascular endothelium at sites of endothelial injury where extracellular matrix (ECM) components in the sub-endothelial space are exposed to the circulation. GP family glycoproteins mediate rapid tethering to ECM molecules at these sites. Integrin heterodimers become activated and then provide robust platelet adhesion....

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