Catalog Number: 4402
Alternate Names: P518, QRFP
Biological Activity
Hypothalamic RFamide-related neuropeptide. Acts as a natural ligand of the orphan receptor GPR103. Exhibits orexigenic acitivity in mice upon central administration.
Technical Data
  • M.Wt:
    2818.18
  • Formula:
    C127H197N37O36
  • Sequence:
    VGTALGSLAEELNGYNRKKGGFSFRF

    (Modifications: Phe-26 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    881640-56-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat.
    Kampe et al.
    Brain Res., 2006;1119:133
  2. Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa
    Le Marec et al.
    J.Med.Chem., 2011;54:4806
  3. Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity.
    Chartrel et al.
    Proc.Natl.Acad.Sci.USA, 2003;100:15247

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