Catalog Number: 1035
Chemical Name: 8-Methoxy-2-propionamidotetralin
Biological Activity
Melatonin receptor agonist, 20-fold selective for the MT2 (vs MT1) subtype. At human recombinant MT1 and MT2 receptors, displays pKi values of 8.23 and 8.95 respectively.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Melatonin receptors: are there multiple subtypes?
    TiPS, 1995;16:50
  2. Pharmacological characterization of human recombinant melatonin mt1 and MT2 receptors.
    Browning et al.
    Br.J.Pharmacol., 2000;129:877
  3. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor.
    Dubocovich et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1997;355:365
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