ACV 1

  ( 1 citations )    
Product Datasheet
Catalog Number:3205
Alternate Names:Conotoxin Vc1.1
Chemical Name:
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Neuronal nicotinic receptor antagonist that displays selectivity for the α9α10 subtype (IC50 values are 19, 140, 980, 4200 and 7300 nM for α9α10, α6/α3β2β3, α6/α3β4, α3β4 and α3β2 subtypes respectively). Alleviates neuropathic pain in three rat models of human neuropathic pain and accelerates functional recovery of injured neurons.
Technical Data
  • M.Wt:
    1806.98
  • Formula:
    C71H103N23O25S4
  • Sequence:
    GCCSDPRCNYDHPEIC

    (Modifications: Cys-16 - C-terminal amide, Disulfide bridge between 2 - 8, 3 - 16)

  • Storage:
    Store at -20°C
  • CAS No:
    740980-24-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from Dr Bruce Livett
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for ACV 1 include:

1 Citations: Showing 1 - 1

  1. Re-Emergent Inhibition of Cochlear Inner Hair Cells in a Mouse Model of Hearing Loss.
    Authors: Zachary and Fuchs
    J Neurosci  2015;35:9701

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