Chemical Name:4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[220.127.116.11,7]dec-1-yl ester
Biological Activity p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3 nM) in vitro. Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Desiccate at +4°C
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