Adaphostin

Catalog # Availability Size / Price Qty
3716/10
3716/50
Abl Kinase Inhibitors Small Molecule
1 Image
Description: p210bcr/abl kinase inhibitor
Alternative Names: NSC 680410

Chemical Name: 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13,7]dec-1-yl ester

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3 nM) in vitro. Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro.

Technical Data

M.Wt:
393.48
Formula:
C24H27NO4
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
241127-58-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Adaphostin

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