Human form of the predominant amyloid β
-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic. Control peptide
(Cat. No. 3391) also available.
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All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders.
Van Nostrand et al.
Amyloid beta peptide of Alzheimer's disease downregulates bcl-2 and upregulates bax expression in human neurons.
Paradis et al.
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Glenner and Wong
The citations listed below are publications that use Tocris products. Selected citations for Amyloid β-Peptide (1-42) (human) include:
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