Rat form of the predominant amyloid β
-peptide found in plaques associated with Alzheimer's disease. Leads to a large shift in the bax/bcl-2 ratio in favour of pro-apoptotic bax. Neurotoxic.
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Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders.
Van Nostrand et al.
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Glenner and Wong
The citations listed below are publications that use Tocris products. Selected citations for Amyloid β-peptide (1-42) (rat) include:
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