Inactive control peptide for amyloid β-peptide (1-42)
(Cat. No. 1428), the predominant form of amyloid β
-peptide found in the brains of patients with Alzheimer's disease.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Amyloid-beta peotide is toxic to neurons in vivo via indirect mechanisms.
Walsh et al.
Mitochondrial respiratory inhibition and oxidative stress elevate β-secretase (BACE1) proteins and activity in vivo in the rat retina.
Xiong et al.
Exp.Brain Res., 2007;181:435
Proteomic identification of proteins oxidized by Aβ(1-42) in synaptosomes: Implications for Alzheimer's disease.
Boyd-Kimball et al.
Brain Res., 2005;1004:206
The citations listed below are publications that use Tocris products. Selected citations for Amyloid β-peptide (42-1) (human) include:
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