Biological Activity
Selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Antagonistic properties of [Phe3,Leu13]porcine motilin.
Depoortere et al.
Eur.J.Pharmacol., 1995;286:241 -
The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
Peeters et al.
Biochem.Biophys.Res.Commun., 1994;198:411
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