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ANQ 11125

5074 Datasheet / COA / SDS

Discontinued Product

5074 has been discontinued.
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ANQ 11125
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Description: Selective motilin receptor antagonist
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Biological Activity

ANQ 11125 is a selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data

M.Wt:
1761.05
Formula:
C86H125N19O21
Sequence:
FVFIFTYGELQRLQ
Storage:
Store at -20°C
CAS No:
153966-48-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Antagonistic properties of [Phe3,Leu13]porcine motilin.
    Depoortere et al.
    Eur.J.Pharmacol., 1995;286:241
  2. The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
    Peeters et al.
    Biochem.Biophys.Res.Commun., 1994;198:411

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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