ANQ 11125

Catalog # Availability Size / Price Qty
5074/1
Cat.No. 5074 - ANQ 11125 | Phe-Val-Phe-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln | CAS No. 153966-48-4
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Description: Selective motilin receptor antagonist
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Biological Activity

Selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data

M.Wt:
1761.05
Formula:
C86H125N19O21
Sequence:
FVFIFTYGELQRLQ
Storage:
Store at -20°C
CAS No:
153966-48-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Antagonistic properties of [Phe3,Leu13]porcine motilin.
    Depoortere et al.
    Eur.J.Pharmacol., 1995;286:241
  2. The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
    Peeters et al.
    Biochem.Biophys.Res.Commun., 1994;198:411

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