Biological ActivityANQ 11125 is a selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Antagonistic properties of [Phe3,Leu13]porcine motilin.
Depoortere et al.
The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit.
Peeters et al.
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