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Catalog Number:5035
Chemical Name:2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoic acid
Product Details
Supplemental Products
Reviews
Biological Activity
Selective free fatty acid receptor 1 (FFA1/GPR40) agonist. Exhibits selectivity for GPR40 over GPR41, GPR43, GPR119, GPR120 and PPARγ. Induces glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo. Enhances insulin sensitivity in a type 2 diabetes model in vivo. Orally available.
Selective free fatty acid receptor 1 (FFA1/GPR40) agonist. Exhibits selectivity for GPR40 over GPR41, GPR43, GPR119, GPR120 and PPARγ. Induces glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo. Enhances insulin sensitivity in a type 2 diabetes model in vivo. Orally available.
Technical Data
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M.Wt:448.53
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Formula:C27H29FN2O3
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Solubility:Soluble to 50 mM in DMSO and to 20 mM in ethanol
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Purity:>98
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Storage:Store at +4°C
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CAS No:1030846-42-4
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
VersaClone cDNA Plasmids
Description
Application
Cat#
Citations
Images
Human FFAR1/GPR40 (NP_005294) VersaClone cDNA
RDC0272
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Human FFAR1/GPR40 (AAI20945) VersaClone cDNA
RDC0136
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Mouse FFAR1/GPR40 (NP_918946) VersaClone cDNA
RDC0516
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