AS 2034178

Catalog # Availability Size / Price Qty
5035/10
5035/50
Cat.No. 5035 - AS 2034178 | C27H29FN2O3 | CAS No. 1030846-42-4
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Description: Selective FFA1 (GPR40) agonist

Chemical Name: 2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoic acid

Purity: ≥98%

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Biological Activity

Selective free fatty acid receptor 1 (FFA1/GPR40) agonist. Exhibits selectivity for GPR40 over GPR41, GPR43, GPR119, GPR120 and PPARγ. Induces glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo. Enhances insulin sensitivity in a type 2 diabetes model in vivo. Orally available.

Technical Data

M.Wt:
448.53
Formula:
C27H29FN2O3
Solubility:
Soluble to 50 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1030846-42-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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