AS 2034178

   
Product Datasheet
Catalog Number:5035
Chemical Name:2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoic acid
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Biological Activity
Selective free fatty acid receptor 1 (FFA1/GPR40) agonist. Exhibits selectivity for GPR40 over GPR41, GPR43, GPR119, GPR120 and PPARγ. Induces glucose-dependent insulin secretion in pancreatic MIN6 cells and in vivo. Enhances insulin sensitivity in a type 2 diabetes model in vivo. Orally available.
Technical Data
  • M.Wt:
    448.53
  • Formula:
    C27H29FN2O3
  • Solubility:
    Soluble to 50 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    1030846-42-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
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Human FFAR1/GPR40 (NP_005294) VersaClone cDNA

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Mouse FFAR1/GPR40 (NP_918946) VersaClone cDNA

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