C-type natriuretic peptide (1-22) (human, rat, swine)

  ( 1 citations )    
Product Datasheet
Catalog Number:3520
Chemical Name:
Product Details
Citations (1)
Reviews
Biological Activity
Endogenous peptide found in plasma and cerebrospinal fluid. Behaves as an agonist at natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). Inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo.
Technical Data
  • M.Wt:
    2197.61
  • Formula:
    C93H157N27O28S3
  • Sequence:
    GLSKGCFGLKLDRIGSMSGLGC

    (Modifications: Disulfide bridge between 6 - 22)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    127869-51-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for C-type natriuretic peptide (1-22) (human, rat, swine) include:

1 Citations: Showing 1 - 1

  1. Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats.
    Authors: Stott Et al.
    Hypertension  2015;65:676

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