Biological ActivityCocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response.
(Modifications: Disulfide bridge between 14 - 32, 20 - 40, 34 - 47)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
CART, a new anorectic peptide.
Thim et al.
Int.J.Biochem.Cell Biol., 1998;30:1281
Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold.
Ludvigsen et al.
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