Immune Cell Differentiation and Expansion Kits

Our CellXVivo™ Immune Cell Differentiation and Expansion Kits include optimized cytokine combinations and protocols for the differentiation and expansion of dendritic cells, T helper cell subtypes, regulatory T cells, and B cells.

 

Benefits

  • Guaranteed to produce consistent and reliable results
  • Efficient immune cell differentiation
  • Cost-effective and time-saving
  • Conveniently packages all reagents needed for immune cell differentiation or expansion

Features

  • Includes optimized combinations of R&D Systems® high-quality proteins and antibodies
  • Simple and optimized protocols
  • Quality controlled for consistency and reliability
  • Does not require specialized instrumentation

 

CellXVivo™ Myeloid Differentiation Kits

Human Monocyte-Derived Dendritic Cell Differentiation Kit

Differentiates CD14+ monocytes into monocyte-derived dendritic cells.

Mouse Dendritic Cell Differentiation Kit New!

Differentiates mouse bone marrow cells into  dendritic cells.

Human M1 Macrophage Differentiation Kit 

Differentiates CD14+ monocytes into M1 macrophage cells.

Human M2 Macrophage Differentiation Kit 

Differentiates CD14+ monocytes into M2 macrophage cells.

CellXVivo™ Lymphocyte Differentiation Kits

Human Th1 Cell Differentiation Kit

Differentiates naïve CD4+ lymphocytes into mature Th1 effector cells.

Mouse Th1 Cell Differentiation Kit New!

Differentiates naïve CD4+ mouse lymphocytes into Th1-polarized effector cells.

Human Th2 Cell Differentiation Kit

Differentiates naïve CD4+ lymphocytes into mature Th2 effector cells.

Mouse Th2 Cell Differentiation Kit New!

Differentiates naïve CD4+ mouse lymphocytes into Th2-polarized effector cells.

Human Th17 Cell Differentiation Kit

Differentiates naïve CD4+ lymphocytes into mature Th17 effector cells.

Mouse Th17 Cell Differentiation Kit New!

Differentiates naïve CD4+ mouse lymphocytes into Th17-polarized effector cells.

Human Treg Cell Differentiation Kit

Differentiates naïve CD4+ human lymphocytes into CD25+FoxP3+ regulatory T cells.

Mouse Treg Cell Differentiation Kit

Differentiates naïve CD4+ mouse lymphocytes into CD25+FoxP3+ regulatory T cells.

CellXVivo™ Lymphocyte Expansion Kits

Human NK Cell Expansion Kit New!

Expands human CD3-CD56+ cytokine-induced killer (CIK) cell populations from PBMCs.

Human CIK Cell Expansion Kit New!

Expands human CD3+CD56+ cytokine-induced killer (CIK) cell populations from PBMCs.

Human B Cell Expansion Kit

Expands human B cell populations.

Cell Activation Reagents

Cell Activation Cocktail

A 500X cocktail of Monensin, PMA, and Ionomycin for activating immune cells.

Leukocyte maturation into immune effector cell types occurs in vivo following immune insults or injuries, making it challenging to harvest populations of mature human immune cells without significant variability. In an effort to simplify and reduce variability during the procurement of mature leukocyte populations, R&D Systems offers CellXVivo™ kits to expand and differentiate mature lymphoid and myeloid immune cell types from enriched populations of peripheral blood mononuclear cells (PBMCs). These kits contain the high-quality reagents and optimized protocols needed to drive efficient differentiation or expansion. CellXVivo™ Immune Cell Differentiation and Expansion Kits are developed and optimized to be used in conjunction with our MagCellect™ Cell Selection Kits.