Dissolvable Microspheres for Immune Cell Expansion in Cell Therapy
The robust ex vivo expansion of immune cells is a pivotal technique for the development and success of immune cell culture and immune cell therapies. R&D Systems is proud to provide a magnetic-free bead-based technology for the robust and reliable expansion of immune cells. Our pioneering Cloudz™ expansion technology provides a simple protocol for the expansion of several types of immune cells including T cells, NK cells, and Treg cells. The Cloudz expansion technology is:
Simple
Fast, easy cell harvesting with addition of release buffer
Magnetic-Free
Avoid additional processing that causes greater cell loss
Optimized
Ready to use with cytokines, growth factors and media from R&D Systems
GMP Cloudz™ Human T Cell Activation Kit
T cells can be used as a powerful immunotherapy to fight against cancer and other diseases. The GMP Cloudz Human T Cell Activation Kit utilizes dissolvable CD3/CD28 microspheres that can easily be removed from expanded cell cultures. The GMP Cloudz Human T Cell Activation kit supports the expansion of human T cell lines or T cell clones and the stimulation of human peripheral blood lymphocytes.
- >50-fold expansion of T cells from PBMCs in 10 days
- Dissolvable CD3/CD28 microspheres enable T cell expansion
- Optimized for use with ExCellerate™ Human T Cell Media
- Supports T cell expansion from PBMCs or purified CD3+ PBMCs
- Optimized for use with R&D Systems™ GMP cytokines and media
Cloudz™ Human NK Cell Expansion Kit
Natural killer cells are innate lymphoid cells with intrinsic cytoxic and cytokine producing capabilities that play an important role in infection, autoimmunity, and tumor immunosurveillance. The Cloudz Human NK Cell Expansion Kit provides a feeder-free expansion protocol that selectively expands NK cells from peripheral blood mononuclear cells (PBMCs).
- Magnetic-free microsphere technology reduces cell loss and unknown variables in your cell cultures
- Robust, >100-fold expansion of NK cells in 10 days
- Optimized for use with R&D Systems™ cytokines and media
Cloudz™ Human Regulatory T Cell (Treg) Expansion Kits
Both GMP and RUO versions available
Regulatory T cells, also known as suppressor cells, are a subset of CD4+ T cells that maintain immune homeostasis by suppressing immune responses and controlling autoimmune recognition. The Cloudz Human Treg Expansion Kits provide robust expansion of FoxP3+ human Treg cells from CD4+ T cells.
- Magnetic-free dissolvable microsphere technology reduces cell loss and unknown variables in your cell cultures
- 500-fold expansion of FoxP3+ Treg cells in 9 days
- Optimized for use with R&D Systems™ cytokines and media
