Biological Activity Non-competitive NMDA receptor antagonist (IC50 = 0.4 μM). Inhibits Ca2+ influx and glutamate-induced toxicity in central nervous system neurons. Exhibits age-dependent physiological effects; induces a sleep-like state in young mice and hyperactivity in older mice.
(Modifications: X = Gla, Ala-21 = C-terminal amide)
Store at -20°C
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