COVID-SeroIndex, Kantaro SARS-COV-2 IgG Antibody IVD Kit

Available in the EU and UK only. For research testing

COVID-SeroIndex (100% seroprevelance)

Configured to support vaccine development, this kit enables testing for populations expecting a 100% seroprevalence. The COVID-SeroIndex ELISA is a quantitative IgG antibody kit that enables an objective measurement of SARS-CoV-2 antibodies - indicative of a prior COVID-19 infection.
Product Details

COVID-SeroIndex, Kantaro SARS-COV-2 IgG Antibody IVD Kit Summary

Sample Type & Volume Required Per Well Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)
Sensitivity 3.2 AU/mL
Assay Range 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma)
Specificity Natural and recombinant human anti-SARS-CoV-2 IgG
Cross-reactivity < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference No significant interference observed with available related molecules.

Product Summary

COVID-SeroIndex is a 2-phase ELISA optimized for accurate detection of SARS-CoV-2 IgG antibodies, present in human plasma or serum samples. Validation studies have demonstrated a specificity a PPA of 97.8% and an NPA of 99.6%. Sufficient reagents are provided to test 360 samples per kit.

Phase 1 is a qualitative ELISA in which negative samples are eliminated from further analysis. Phase 2 is a quantitative ELISA confirming positive samples and providing an antibody titer for SARS-CoV-2 IgG antibodies present in the sample.

Performance Characteristics:

Analytical Measuring Range 3.2 – 160 AU/mL
Linear Range 3.1 – 160 AU/mL
Within-Site Imprecision See product datasheet for details.
Lot-to-Lot Imprecision See product datasheet for details.
Site-to-Site Reproducibility See product datasheet for details.
Analytical Sensitivity 3.20 AU/mL (see product datasheet for additional information)
Positive Percent Agreement 97.8%
Negative Percent Agreement 99.6%
Antibody Class Specificity See product datasheet for details.

Background: SARS-CoV-2


Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Product Datasheets

Background: Spike RBD

The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.

Long Name
Spike Receptor Binding Domain
Entrez Gene IDs
3200426 (HCoV-HKU1); 14254594 (MERS-CoV); 1489668 (SARS-CoV); 43740568 (SARS-CoV-2)
Alternate Names
Spike RBD


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