Catalog Number: 1913
Biological Activity
Bombesin receptor antagonist; inhibits bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Centrally active in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: X = Glp, Phe-12 = D-Phe, Gly-14 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. [d-Phe12]bombesin analogues: a new class of bombesin receptor antagonists.
    Heinz-Erian et al.
    Am.J.Physiol., 1987;252:G439
  2. Localization of receptors for bombesin-like peptides in the rat brain.
    Moody et al.
    Ann.N.Y.Acad.Sci., 1988;547:114
  3. (D-Phe12) Bombesin and substance P analogues function as central bombesin receptor antagonists.
    Merali et al.
    Synapse, 1988;2:282
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