EGLU

  ( 5 citations )    
Product Datasheet
Catalog Number:0971
Chemical Name:(2S)-α-Ethylglutamic acid
Product Details
Citations (5)
Reviews
Biological Activity
Selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord; presumed group II mGlu receptor antagonist. Also available as part of the Group II mGlu Receptor Tocriset™.
Technical Data
  • M.Wt:
    175.18
  • Formula:
    C7H13NO4
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Purity:
    >95
  • Storage:
    Store at -20°C
  • CAS No:
    170984-72-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for EGLU include:

5 Citations: Showing 1 - 5
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  1. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
    Authors: Scholler
    Nat Chem Biol  2017;13(4):372
  2. Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors.
    Authors: Ster Et al.
    J Neurosci  2011;108:9993
  3. Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra.
    Authors: Kaushal and Schlichter
    Proc Natl Acad Sci U S A  2008;28:2221
  4. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism.
    Authors: Jiang Et al.
    J Neurosci  2006;26:4318
  5. Pattern-dependent, simultaneous plasticity differentially transforms the input-output relationship of a feedforward circuit.
    Authors: Smith and Otis
    Proc Natl Acad Sci U S A  2005;102:14901

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