Chemical Name: 2-[(4-Fluorobenzoyl)amino]-benzoic acid methyl ester
Biological ActivityExo1 is a reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC50 ~ 20 μM). Has similar, but not identical, action to brefeldin A (Cat. No. 1231).
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Exo1: A new chemical inhibitor of the exocytic pathway.
Feng et al.
Citations for Exo1
The citations listed below are publications that use Tocris products. Selected citations for Exo1 include:
2 Citations: Showing 1 - 2
XE991 and Linopirdine are state-dependent inhibitors for Kv7/KCNQ channels that favor activated single subunits.
Authors: Greene Et al.
Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion.
Authors: Eppler Et al.
PLoS One 2017;12:e0172443
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