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FERb 033

3523 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3523/10
3523/50
FERb 033 | CAS No. 1111084-78-6 | Estrogen and Related Receptor Agonists
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Description: Potent and selective ERβ agonist

Chemical Name: 2-Chloro-3'-fluoro-3,4'-dihydroxy-[1,1-biphenyl]-4-carboxaldehyde oxime

Purity: ≥98%

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Biological Activity

FERb 033 is a potent and selective ERβ receptor agonist (Ki = 7.1 nM, EC50 = 4.8 nM). Displays 62-fold selectivity over ERα.

Technical Data

M.Wt:
281.67
Formula:
C13H9ClFNO3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1111084-78-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Structural evolutions of salicylaldoximes as selective agonists for estrogen receptor β.
    Minutolo et al.
    J.Med.Chem., 2009;52:858

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