Catalog Number: 2696
Biological Activity
Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
Technical Data
  • M.Wt:
    3164.48
  • Formula:
    C141H211N43O41
  • Sequence:
    GWTLNSAGYLLGPHAIDNHRSFSDKHGLT

    (Modifications: Thr-29 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    114547-31-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cloning and expression characterization of a novel galanin receptor.
    Wang et al.
    J.Biol.Chem., 1997;272:51
  2. Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling.
    Mazarati et al.
    J.Pharmacol.Exp.Ther., 2006;318:700
  3. Galanin receptor subtypes.
    Branchek et al.
    TiPS., 2000;21:109
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Galanin (1-29) (rat, mouse) include:

1 Citations: Showing 1 - 1

  1. Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulatecortex of normal rats and rats with mononeuropathy.
    Authors: Zhang
    Sci Rep 2017;7:45930

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