Catalog Number: 1851
Alternate Names: GLP-1 (1-37) amide
Biological Activity
Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 5 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Exon duplication and divergence in the human preproglucagon gene.
    Bell et al.
    Nature, 1983;304:368
  2. Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake.
    Navarro et al.
    J.Neurochem., 1996;67:1982
  3. Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells.
    Suzuki et al.
    Proc.Natl.Acad.Sci.USA, 2003;100:5034

The citations listed below are publications that use Tocris products. Selected citations for Glucagon-like peptide 1 (1-37) (human, rat) include:

Showing Results 1 - 1 of 1

  1. The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval.
    Authors: Zhang Et al.
    J Neurosci
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