Catalog Number: 5850
Chemical Name: 2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid
Biological Activity
High affinity FABP4 inhibitor (Ki < 1 nM). Highly selective for FABP4 over FABP3. Inhibits LPS-induced activation of murine macrophages in vitro.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein.
    Liu et al.
    Bioorg.Med.Chem.Lett., 2011;21:2949
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