|Detection of CLEC14A in Human Umbilical Vein Endothelial Cells by Flow Cytometry. Human umbilical vein endothelial cells were stained with Mouse Anti-Human CLEC14A PE‑conjugated Monoclonal Antibody (Catalog # FAB7436P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.|
CLEC14A (C-type lectin domain family 14 member A; also called EGFR5) is a 51 kDa (predicted) member of the C-type lectin domain family of proteins. It is a type I transmembrane protein, apparently expressed in brain and about which little is known. Mature human CLEC14A is 469 amino acids in length. It contains a 376 aa extracellular region (aa 22-397) and a 72 aa cytoplasmic domain. The extracellular region shows one C-type lectin like domain (aa 32-175) and an EGF-like region (aa 245-287). Over aa 22-397, human CLEC14A shares 66% and 81% aa identity with mouse and canine CLEC14A, respectively.
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