Human Complement Component C1qC Alexa Fluor® 350-conjugated Antibody

Catalog #: AF3337U Datasheet / COA / SDS

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AF3337U-100UG

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Human Complement Component C1qC Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Complement C1qC in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) C1qA and rhC1qB is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human C1qC
Lys115-Asp245
Accession # P02747

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Complement Component C1qC

C1qC is a globular secreted protein and is a subunit of complement component C1q. C1q is composed of 18 polypeptide chains of three distinct subtypes (C1qA, C1qB and C1qC) arranged as 6 disulfide-linked A-B heterodimers and 3 disulfide-linked C-C homodomers. All C1q subunits contain a C1q globular domain and one collagen-like domain. C1q is a subcomponent of complement C1 complex which comprises one C1q and the Ca²⁺-dependent serine protease tetramer C1r₂-C1s₂. C1 complex triggers the classical complement pathway. Within the C1q domain, human C1qC shares approximately 75% amino acid sequence identity with mouse and rat C1qC.

Long Name

Complement Component 1q Subcomponent Subunit C Precursor

Entrez Gene IDs

714 (Human)

Alternate Names

C1qC; C1Q-C; C1QGcomplement component 1, q subcomponent, gamma polypeptide; complement C1q subcomponent subunit C; complement component 1, q subcomponent, C chain; Complement Component C1qC; FLJ27103