Human Complement Component C1rLP Alexa Fluor® 647-conjugated Antibody

Catalog #: AF3676R Datasheet / COA / SDS

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AF3676R-100UG

All Complement Component C1rLP Antibodies

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Human Complement Component C1rLP Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse C1rLP is observed and less than 5% cross-reactivity with recombinant

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Complement Component C1rLP
Ser41-Asn487
Accession # AAI56781

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Complement Component C1rLP

C1rLP, also known as CLSPa, is a plasma serine protease that is related to the C1r complement component. C1rLP is a 487 amino acid protein that contains one CUB domain and a serine protease domain. C1rLP activates pro-C1s and pro-haptoglobin but also inhibits complement-mediated cytotoxicity. Human and mouse C1rLP share 73% aa sequence identity.

Long Name

Complement C1r Subcomponent-like Protein

Entrez Gene IDs

51279 (Human); 232371 (Mouse)

Alternate Names

C1RL; C1RL1; C1RL1complement C1r subcomponent-like protein; C1r-like protein; C1r-like serine protease analog protein; C1r-LPcomplement C1r-like proteinase; C1RLPEC 3.4.21.-; CLSPa; complement component 1, r subcomponent-like; Complement Component C1rLP; EC 3.4.21; EC 3.4.21.41