Detection of DCIR/CLEC4A in Human Blood Neutrophils by Flow Cytometry.
Human peripheral blood neutrophils were stained with Mouse Anti-Human DCIR/CLEC4A Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1748F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family, and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) in its cytoplasmic domain. Besides its association with dendritic cells, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.
Dendritic Cell Immunoreceptor
Entrez Gene IDs:
50856 (Human); 26888 (Mouse)
CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIR; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR
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