Human GHSR APC-conjugated Antibody

FAB8370A has been discontinued. View all GHSR products.
    
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  • Species Reactivity
    Human
  • Specificity
    Detects GHSR on transfectants by flow cytometry.
  • Source
    Monoclonal Mouse IgG1 Clone # 502430
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human GHSR
    Accession # NP_940799
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Allophycocyanin
Product Datasheets

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Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Detection of GHSR in HEK293 Human Cell Line Transfected with Human GHSR and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human GHSR and eGFP was stained with either (A) Mouse Anti-Human GHSR APC‑conjugated Monoclonal Antibody (Catalog # FAB8370A) or (B) Mouse IgG1 Allophycocyanin Isotype Control (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: GHSR
GHSR is a member of the G protein-coupled receptor family that may play a role in energy homeostasis and regulation of body weight. Two conserved transcript variants for GHSR are expressed in several tissues. This transcript, 1a, excises an intron and encodes the functional protein. GHSR is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. Mutations in GHSR are associated with autosomal idiopathic short stature.
  • Long Name:
    Growth Hormone Secretagogue Receptor
  • Entrez Gene IDs:
    2693 (Human); 208188 (Mouse); 84022 (Rat)
  • Alternate Names:
    GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHSR; GHS-R; growth hormone secretagogue receptor type 1; growth hormone secretagogue receptor
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