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Human GLI-1 ExactaChIP Chromatin IP Kit

Catalog #: ECP3324
1 Citation Datasheet / COA / SDS

Discontinued Product

ECP3324 has been discontinued.
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Human GLI-1 ExactaChIP Chromatin IP Kit Summary

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Product Datasheet
COA
SDS

Background: GLI-1

GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.

Long Name
Glioma-Associated Oncogene Homolog 1 [Zinc Finger Protein]
Entrez Gene IDs
2735 (Human); 14632 (Mouse); 140589 (Rat)
Alternate Names
GLI family zinc finger 1; GLI1; GLI-1; glioma-associated oncogene family zinc finger 1; glioma-associated oncogene homolog 1 (zinc finger protein); Glioma-associated oncogene; GLIzinc finger protein GLI1; Oncogene GLI

Citation for Human GLI-1 ExactaChIP Chromatin IP Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.
    Authors: Kurita S, Mott JL, Almada LL
    Oncogene, 2010;29(34):4848-58.  2010

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