Human GLI-2 ExactaChIP Chromatin IP Kit
Human GLI-2 ExactaChIP Chromatin IP Kit Summary
GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI3 functions primarily as a repressor of Hh target gene expression, while GLI-1 and GLI-2 are activators that promote Hh signaling.
Citations for Human GLI-2 ExactaChIP Chromatin IP Kit
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GLI2 Regulates TGF-beta1 in Human CD4(+) T Cells: Implications in Cancer and HIV Pathogenesis.
Authors: Furler RL, Uittenbogaart CH
PLoS ONE, 2012;7(7):e40874. 2012
GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment.
Authors: Elsawa SF, Almada LL, Ziesmer SC, Novak AJ, Witzig TE, Ansell SM, Fernandez-Zapico ME
J. Biol. Chem., 2011;286(24):21524-34. 2011
GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.
Authors: Kurita S, Mott JL, Almada LL
Oncogene, 2010;29(34):4848-58. 2010
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