Human GLI-2 ExactaChIP Chromatin IP Kit

Discontinued Product

ECP3526 has been discontinued.
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Product Details
Citations (3)
FAQs
Reviews

Human GLI-2 ExactaChIP Chromatin IP Kit Summary

GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI3 functions primarily as a repressor of Hh target gene expression, while GLI-1 and GLI-2 are activators that promote Hh signaling.

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: GLI-2

Long Name
GLI-Kruppel family member GLI2
Entrez Gene IDs
2736 (Human); 14633 (Mouse); 304729 (Rat)
Alternate Names
GLI family zinc finger 2; GLI2; GLI-2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9tax helper protein 1; oncogene GLI2; tax helper protein 2; Tax helper protein; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; THP; THP1; THP2; zinc finger protein GLI2

Reagents Provided

Citations for Human GLI-2 ExactaChIP Chromatin IP Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. GLI2 Regulates TGF-beta1 in Human CD4(+) T Cells: Implications in Cancer and HIV Pathogenesis.
    Authors: Furler RL, Uittenbogaart CH
    PLoS ONE, 2012;7(7):e40874.  2012
  2. GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment.
    Authors: Elsawa SF, Almada LL, Ziesmer SC, Novak AJ, Witzig TE, Ansell SM, Fernandez-Zapico ME
    J. Biol. Chem., 2011;286(24):21524-34.  2011
  3. GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.
    Authors: Kurita S, Mott JL, Almada LL
    Oncogene, 2010;29(34):4848-58.  2010

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