Detection of GPR39 in NS0 Mouse Cell Line Transfected with Human GPR39 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human GPR39 was stained with Mouse Anti-Human GPR39 PE‑conjugated Monoclonal Antibody (Catalog # FAB3348P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane G-protein coupled glycoprotein that is a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39.
G Protein-coupled Receptor 39
Entrez Gene IDs:
2863 (Human); 71111 (Mouse); 288995 (Rat)
G protein-coupled receptor 39; GPR39; G-protein coupled receptor 39; MGC149541
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