Human GPR39 PE-conjugated Antibody

FAB3348P has been discontinued. View all GPR39 products.
  
  • Species Reactivity
    Human
  • Specificity
    Detects human GPR39. Stains human GPR39 transfected cells but not irrelevant transfectants.
  • Source
    Monoclonal Mouse IgG2A Clone # 189702
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human GPR39
    Met1-Val453
    Accession # BAG37409
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of GPR39 in NS0 Mouse Cell Line Transfected with Human GPR39 by Flow Cytometry. NS0 mouse myeloma cell line transfected with human GPR39 was stained with Mouse Anti-Human GPR39 PE‑conjugated Monoclonal Antibody (Catalog # FAB3348P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: GPR39

G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane G-protein coupled glycoprotein that is a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39.

  • Long Name:
    G Protein-coupled Receptor 39
  • Entrez Gene IDs:
    2863 (Human); 71111 (Mouse); 288995 (Rat)
  • Alternate Names:
    G protein-coupled receptor 39; GPR39; G-protein coupled receptor 39; MGC149541
Related Research Areas

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