Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are
available in the Technical Information section on our website.
Preparation and Storage
Background: Forkhead Box P3
Human FOXP3 is a 47 kDa member of the P subclass of the forkhead box family of transcription factors. It contains a Leu-rich repeat, a C2H2 zinc finger region, and a C-terminal FKH (forkhead) DNA-binding domain. In human, FOXP3 is found in CD4+, CD8+ and CD4+CD25+ T cells and directly associates with NFAT and NFkB, suppressing their activity in CD4+ T cells.
Forkhead Box P3
Entrez Gene IDs:
50943 (Human); 20371 (Mouse);
AIIDMGC141961; forkhead box P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; JM2; PIDXMGC141963; Scurfin; SCURFIN; scurfin; XPIDpolyendocrinopathy, enteropathy, X-linked
Related Research Areas
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