Detection of Neuritin in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Neuritin Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB283R, filled histogram) or isotype control antibody (Catalog # IC0041R, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Neuritin (NRN1) is a 14 kDa GPI-linked molecule that is expressed on developing and differentiating neurons, as well as hepatocytes and Schwann cells. Neuritin is upregulated in response to BDNF, NT-3, androgens, and hypoxia, and it promotes neuronal migration, neurite extension, and arborization. Neuritin does contribute to the formation of the ionotrophic glutamate receptor APMA. Here, it is a component of the outer core. Mature human Neuritin shares 99% and 100% amino acid sequence identity with mouse and rat Neuritin, respectively.