Human P2Y1/P2RY1 PE-conjugated Antibody Summary
Accession # NP_002554
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of P2Y1/P2RY1 in HEK293 Human Cell Line Transfected with Human P2Y1/P2RY1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human P2Y1/P2RY1 and eGFP were stained with (A) Mouse Anti-Human P2Y1/P2RY1 PE-conjugated Monoclonal Antibody (Catalog # FAB9290P) or (B) isotype control antibody (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
P2RY1 belongs to the family of G protein-coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. P2RY1 functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C. ADP binding also may lead to a change in platelet shape and possible platelet aggregation.
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