Human PPAR gamma /NR1C3 Antibody
Human PPAR gamma /NR1C3 Antibody Summary
Amino Acids 3-108
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
Background: PPAR gamma/NR1C3
Peroxisome Proliferator-Activated Receptor gamma (PPAR gamma ; NR1C3) is a member of the orphan nuclear receptor family. Oxidized metabolites of linoleic acid, 9-hydroxyctadienoic acid (9-HODE) and 13-HODE are activators and ligands of PPAR gamma. PPAR gamma is expressed in white adipose tissue, intestinal mucosa, colon, spleen, monocytes, macrophages, retina, cartilage, osteoclasts, and skeletal muscle. PPAR gamma plays important roles in lipid and glucose metabolism and has been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three known family members are called PPAR alpha, δ, and gamma. Three N-terminal isoforms, called gamma 1, gamma 2 and gamma 3, are known to arise by alternative splicing and promoter usage from the PPAR gamma gene. RXR is an obligate partner for PPAR.
Citation for Human PPAR gamma /NR1C3 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1?
Authors: S Basu, K Gnanaprade, T Barnoud, CP Kung, M Tavecchio, J Scott, A Watters, Q Chen, AV Kossenkov, ME Murphy
Genes Dev., 2018;0(0):.
Sample Types: Whole Cells
Applications: Proximity Ligation Assay (PLA)
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