Human Sortilin Alexa Fluor® 405-conjugated Antibody Summary
Accession # Q99523
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
R&D Systems Antibodies
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Sortilin, also known as neurotensin receptor 3, is a 100 kDa transmembrane receptor that is localized both in the endosomal compartment and on plasma membranes. It contains an extracellular/lumenal Vps10p (vacuolar protein-sorting 10 protein) domain and is one of five known members of the mammalian Vps10p-D receptor family. A Sortilin propeptide, cleaved by a furin, blocks premature ligand binding to uncleaved Sortilin and functions as a chaperone to facilitate trafficking in the Golgi compartments. Sortilin binds multiple ligands and has diverse functions. Mature human Sortilin extracellular domain shares 92% and 91% amino acid sequence identity with that of mouse and rat Sortilin, respectively.
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Reviews for Human Sortilin Alexa Fluor® 405-conjugated Antibody
There are currently no reviews for this product. Be the first to review Human Sortilin Alexa Fluor® 405-conjugated Antibody and earn rewards!
Have you used Human Sortilin Alexa Fluor® 405-conjugated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image